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KMID : 0351219950270040407
Korean Journal of Infectious Diseases
1995 Volume.27 No. 4 p.407 ~ p.412
A Case of Neonatal Herpes Simplex Virus encephalitis
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Abstract
Herpes simplex virus infection(HSV) during the neonatal period is associated with high mortality and morbidity. Neonatal HSV encephalitis frequently manifests as disseminated herpetic viral infection or localized herpeic central nervous system
infection. HSV encephalitis in neonates shows progressive central nervous system manifestations affecting predominantly temporal and frontal lobes. The early diagnosis of HSV encephalitis is essential, because untreated or delayed cases suffer
from
poor
prognosis with high mortality. We experienced a case of HSV encephalitis in a 28-day old boy who presented with fever and seizure. The diagnosis was supported by electroencephalographic findings and confirmed by serologic tests. Antiviral therapy
was
started soon and the patient responded well. Follow-up of the patient is still being carried out, who is showing normal de- velopment. We report the case with brief review of related literature.
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